Jianzhen Zhang (Professor)
Email：zjz@sxu.edu.cn
Tel：0351-7018871
Dr, Jianzhen Zhang, born on 1971 in Shanxi Province, China, is a professor, doctoral supervisor, and the Deputy Director of Institute of Applied Biology, Shanxi University. She has a long and multifarious career in education, research and administration. Dr, Zhang won Shanxi Provincial outstanding Young Academic Leaders award and Innovative Talents award, Young Talent of Shanxi University and Taiyuan Science and Technology Top Talent Program.
RESEARCH INTERESTS:
1. Insect molecular toxicology
2. Mechanism of insect cuticle formation and research of a new target in pest control
3. Molecular mechanisms of insect RNA interference efficiency and research of a new technique in pest control
EDUCATION AND WORK EXPERIENCE:
1997 to date: Lecture then Associate professor, Professor, Shanxi University
2010.7-2012.7 Postdoctor, Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences
2003.10-2003.11 Advanced study, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
2001.9-2006.7 PhD, Shanxi University
1994.9-1997.7 MSc, Yangzhou University
1990.9-1994.7 BSc, Shanxi Agricultural University
ABROAD EXPERIENCE:
2017.7-2018.8 Visiting Scholar, Kansas State University, United States
2015.6-2015.9 Senior Visiting Scholar (Funded by Shanxi Provincial Administration for Study Abroad), Tubingen
University, Germany
2008.2-2009.6 Postdoctoral Research (fully funded by the National Council for Study Abroad), Kansas State University,
USA
2004.8-2005.12 Visiting Scholar (Co-Graduate Doctorate), Kansas State University, USA
TEACHING RESPONSIBILITIES:
2007 to date Advanced Molecular Biology (Postgraduate Basic Course)
2000 to date Food Chemistry (Basic Course for Undergraduate Students in Bioengineering)
MEMBERSHIPS:
1. Member of the First Academic Committee of Key Laboratory of Shanxi Province on "Integrated Management of Agricultural Pests"
2. Member of the Professional Committee of Entomological Genomics of the Chinese Entomological Society
3. Member of the Professional Committee of Development and Genetics of the Chinese Entomological Society
4. Council member of Shanxi Entomological Society
KEY PROJECTS:
1. National Natural Science Foundation of China Key Project: Study on the Difference Mechanism of RNA Interference Efficiency of Important Agricultural Pests, 31730074, 2018.1-2022.12
2. Sino-German International Cooperation Project: Mechanism of the Formation of Epidermal Lipids and Its Effect on Insect Ecological Adaptability, 31761133021, 2018.1-2020.12
3. The 13th Five-Year National Key R&D Program Project: Screening of Efficient Safety Target Gene and Mechanism of RNAi, 2017YFD0200904, 2017.7-2020.12
4. National Natural Science Foundation Project: Key Genes Involved in the Ordered Arrangement of Chitin in Insect Epidermis, 31672364, 2017.1-2020.12
HONORS AND AWARDS:
1. Science and Technology Awards of Shanxi Province, September 2017 (second prize in natural sciences)
Project title: Molecular toxicology and chitin metabolism of important agricultural pests
Co-ordinators: Zhang Jianzhen, Liu Xiaojian, Zhang Jianqin, Zhang Xueyao, Qin Guohua, Ma Enbo
2. Science and Technology Award of Shanxi Province, June 2009 (third prize in natural sciences)
Project title: Molecular Evolution and Molecular Toxicology of Important Economic Insects
Co-ordinators: Ma Enbo, Guo Yaping, Zhang Jianzhen, Zhang Min, Wu Haihua, Yang Meiling
SIGNIFICANT PUBLICATIONS:
1. Yu Z.T., Wang Y.W., Zhao X.M., Liu X.J., Ma E.B, Moussian B, Zhang J.Z★.The ABC transporter ABCH-9C is needed for cuticle barrier construction in Locusta migratoria. Insect Biochem. Mol. Biol. 2017 Aug;87:90-99. doi: 10.1016/j.ibmb.2017.06.005. Epub 2017 Jun 10.
2. Song H.F., Zhang J, Li D, Cooper AMW, Silver K, Li T, Liu X, Ma E, Zhu KY, Zhang J.Z★. A double-stranded RNA degrading enzyme reduces the efficiency of oral RNA interference in migratory locust Insect Biochem. Mol. Biol. 2017 Jul; 86:68-80. doi: 10.1016/j.ibmb.2017.05.008. Epub 2017 May 31.
3. Zhao X, Qin Z, Liu W, Liu X, Moussian B, Ma E, Li S, Zhang J.Z★ Nuclear receptor HR3 controls locust molt by regulating chitin synthesis and degradation genes of Locusta migratoria.Insect Biochem. Mol. Biol. 2017 Nov 4;92:1-11. doi: 10.1016/j.ibmb.2017.11.001. [Epub ahead of print]
4. Li K.X., Zhang X.B, Zuo Y., Liu W.M, Zhang J.Z★, Moussian B. Timed Knickkopf function is essential for wing cuticle formation in Drosophila melanogaster Insect Biochem. Mol. Biol. 2017 Oct;89:1-10. doi: 10.1016/j.ibmb.2017.08.003. Epub 2017 Aug 15.
5. Zhao X, Gou X, Qin Z, Li D, Wang Y, Ma E, Li S, Zhang J.Z★.Identification and expression of cuticular protein genes based on Locusta migratoria transcriptome Sci Rep. 2017 Apr 3;7:45462. doi: 10.1038/srep45462.
6. Zhu K.Y., Merzendorfer H., Zhang W.Q., Zhang J.Z., Muthukrishnan S. Biosynthesis, Turnover, and Functions of Chitin in Insects. Annual Review of Entomology, 2016, 61:177–96.
7. Yang M.L., Wang Y.L., Jiang F., Song T.Q., Wang H.M., Liu Q., Zhang J., Zhang J.Z★, Kang L. miR-71 and miR-263 Jointly Regulate Target Genes Chitin synthaseand Chitinase to Control Locust Molting. PLoS Genetics, 2016, 12(8).
8. Yu R.R., Liu W.M., Li D.Q., Zhao X.M., Ding G.W., Zhang M., Ma E.B., Zhu K.Y., Li S., Moussian B., Zhang J.Z★. Helicoidal organization of chitin in the cuticle of the migratory locust requires the function of thechitin deacetylase 2 enzyme (LmCDA2). The Journal of biological chemistry, 2016.291:24352-24363.(doi: 10.1074/jbc.M116.720581)
9. Yu Z.T., Zhang X.Y., Wang Y.W., Moussian B., Zhu K.Y., Li S., Ma E.B., Zhang J.Z★. LmCYP4G102: An oenocyte-specific cytochrome P450 gene required for cuticular waterproofing in the migratory locust, Locusta migratoria. Scientific Reports, 2016, 6:29980.(3 years average IF = 5.295) (SCI, comprehensive journal 2)
10. Li DQ, Zhang JQ, Wang Y, Liu XJ, Ma EB, Sun Y, Li S, Zhu KY, Zhang JZ.★ Two chitinase 5 genes from Locusta migratoria: Molecular characteristics and functional differentiation. Insect Biochem. Mol. Biol. 58: 46–54. 2015.
11. Liu X.J., Zhang H.H., Li S., Zhu K.Y., Guo Y.P., Ma E.B. and Zhang J.Z.★ 2012.Characterization of a midgut-specific chitin synthase gene (LmCHS2) responsible for biosynthesis of chitin of peritrophic matrix in Locusta migratoria, Insect Biochemistry and Molecular Biology, 42,902-910
12. Zhang J.Z.★,Liu X.J., Zhang J.Q., Li D.Q., Sun Y., Guo Y.P., Ma E.B. and Zhu K.Y. 2010. Silencing of two alternative splicing-derived mRNA variants of chitin synthase 1 gene by RNAi is lethal to the oriental migratory locust. Insect Biochemistry and Molecular Biology, 40:824-833(IF=4.028)